Published Abstracts

PUBLISHED ABSTRACTS

1. Olson, A.B., Hussong,S.A., Sills, A., Kayed, R., Galvan, V. Tau-induced astrocyte senescence: A novel mechanism for neural dysfunction in Alzheimer’s disease. Ladiges, W., Ikeno, Y., Wang, L. et al. Resilience in aging and age-related disease. Abstracts from the 2019 Barshop Conference on Aging[J]. Aging Pathobiology and Therapeutics, 2020, 2(1): 01-13.

2. Banh, A., Hussong, S.A., Van Skike, C., Olson, A.B., Hernandez, S.F., Kayed, R., Galvan, V. Tau-induced endothelial cell impairment as a driver of microvascular dysfunction in Alzheimer’s disease. Ladiges, W., Ikeno, Y., Wang, L. et al. Resilience in aging and age-related disease. Abstracts from the 2019 Barshop Conference on Aging[J]. Aging Pathobiology and Therapeutics, 2020, 2(1): 01-13.

3. Olson, A.B., Hussong,S.A., Kayed, R., Galvan, V. Tau-induced astrocyte senescence: a novel mechanism for neuronal dysfunction in alzheimer’s disease, Innovation in Aging, Volume 3, Issue Supplement_1, November 2019, Pages S91–S92, https://doi.org/10.1093/geroni/igz038.348

4. Hussong, S.A., Van Skike, C.E., Olson, A.B., Hart, M.J., Hernandez, S.F., Banh, A., McAllen, S., Kayed, R. and Galvan, V. (2019), P4‐148: Propagation of soluble tau aggregates in brain microvascular endothelial cells promotes cellular senescence/sasp and blocks enos activation. Alzheimer's & Dementia, 15: P1331-P1331. doi:10.1016/j.jalz.2019.06.3809

5. Olson, A.B, Hussong, S.A., Kayed, R., Galvan, V. Tau-induced astrocyte senescence as a driver of neuronal dysfunction in Alzheimer’s disease. Ladiges W. Barshop Symposium on Aging 2018 Abstracts. Pathobiol Aging Age Relat Dis. 2019;9(Suppl 1):1591258. Published 2019 Mar 19. doi:10.1080/20010001.2019.1591258

6. Van Skike, C.E., Hussong, S.A., Olson, A.B., Hernandez, S.F., Banh, A., DeRosa, N. and Galvan, V. (2018), P4‐063: Neurovascular coupling deficits arise prior to cognitive dysfunction in a mouse model of alzheimer's disease. Alzheimer's & Dementia, 14: P1456-P1457. doi:10.1016/j.jalz.2018.06.2466

7. Olson, A.B, Hussong, S.A., Galvan, V. Tau-induced astrocyte senescence as a driver of neuronal dysfunction in Alzheimer’s disease. Selected Abstracts from the American Aging Association 47th Annual Meeting “Improving Resilience to Delay Aging” Philadelphia, 2018. GeroScience 40, 405–418 (2018). https://doi.org/10.1007/s11357-018-0041-z

8. Van Skike, C.E., Jahrling, J.B., Olson, A.B., Sayre, N.L., Hussong, S.A., Ungvari, Z.I., Lechleiter, J.D., Galvan, V. Inhibition of mTOR protects the blood-brain barrier in models of Alzheimer’s disease and vascular cognitive impairment. American Journal of Physiology-Heart and Circulatory Physiology 2018 314:4, H693-H703

9. Olson, A.B, Hussong, S.A., Jarhling, J.B., Galvan, V. mTOR Regulates PICALM in brain vascular cells. Ladiges W. Barshop Symposium on Aging 2017 Abstracts. Pathobiol Aging Age Relat Dis. 2018;8(1):1444939. Published 2018 Mar 7. doi:10.1080/20010001.2018.1444939

10. Hussong, S.A., Olson, A.B, Hart, M.J, Kayed, R., Galvan, V. Prion-like properties of tau oligomers trigger brain vascular endothelial cell dysfunction. Ladiges W. Barshop Symposium on Aging 2017 Abstracts. Pathobiol Aging Age Relat Dis. 2018;8(1):1444939. Published 2018 Mar 7. doi:10.1080/20010001.2018.1444939

11. Olson, A.B., Jarhling, J.B., Hussong, S.A., Galvan, V. The effect of rapamycin on LRP1 transcytosis of Aβ. Promoting healthy aging: intervening with diet, drugs, or exercise. Pathobiology of Aging & Age- Related Diseases. 2016 ;6:34153. DOI: 10.3402/pba.v6.34153.

12. Jarhling, J.B., Sayre, N., Olson, A.B., Galvan, V. Attenuation of mTOR with rapamycin restores blood–brain barrier integrity and function in aging disease models. Promoting healthy aging: intervening with diet, drugs, or exercise. Pathobiology of Aging & Age- Related Diseases. 2016 ;6:34153. DOI: 10.3402/pba.v6.34153.